70% of the earth's carbon in living biomass exists in land plants, most of it in the form of polysaccharide and phenolic biopolymers in the trunks, stems and roots of vascular plants. For the plant this means coordinating how to get carbon from the air and hydrogen and oxygen from water via the roots, to synthesize sugars in the leaves – the currency that the plant can invest. In each of billions of individual plant cells, tens of thousands of proteins work together to metabolize thousands of molecules to use these sequestered sugars and build stable cell walls, keeping open channels for communication and transport throughout the plant. Underground – in addition to getting water, the roots work to obtain crucial nutrients such as nitrogen and phosphorus, via transporters, specialized structures and enzymes, and through symbiotic partnerships with a wide variety of micro-organisms.   

 

In the African Plant Systems biology for the Bioeconomy programme (APSB) we use systems biology, evo-devo approaches, genome engineering and synthetic biology to study important traits in African plants of ecological and economic importance. This includes how plants acquire, manage and invest sequestered carbon to adapt to low-nutrient environments, and create superior plant biomass. 

 

Research Themes

  • Xylem development and evolution
  • Nitrogen and phosphorus acquisition in the plant tree of life
  • Evolvability in real and simulated phenotypic landscapes

Contact Us

Contact:          Prof. Eshchar Mizrachi

Email:             This email address is being protected from spambots. You need JavaScript enabled to view it.

Telephone:      +27 12 420 2136

New Publications

Tonfack LB, Hussey SG, Veale A, Myburg AA, Mizrachi E. (2019) Analysis of orthologous SECONDARY WALL-ASSOCIATED NAC DOMAIN1 (SND1) promotor activity in herbaceous and woody angiosperms. International Journal of Molecular Sciences 20:4623. 10.3390/ijms20184623
Myburg AA, Hussey SG, Wang JP, Street NR, Mizrachi E. (2019) Systems and Synthetic Biology of Forest Trees: A Bioengineering Paradigm for Woody Biomass Feedstocks. Frontiers in Plant Biology 10:775. 10.3389/fpls.2019.00775
Roodt D, Li Z, Van de Peer Y, Mizrachi E. (2019) Loss of wood formation genes in monocot genomes. Genome Biology and Evolution 7(1):1986-1996. https://bit.ly/2WvIe8V PDF
van der Nest MA, Wingfield MJ, McTaggart AR, Van Wyk S, De Vos L, Trollip C, Santana QC, Naidoo K, Dong TA, Wilken PM, Chan W-Y, Palmer M, Soal NA, Roodt D, Steenkamp ET, Wingfield BD. (2019) Genomic analysis of the aggressive tree pathogen Ceratocystis albifundus. Fungal Biology 10.1016/j.funbio.2019.02.002 PDF
Pinard D, Myburg AA, Mizrachi E. (2019) The plastid and mitochondrial genomes of Eucalyptus grandis. BMC Genomics 20(132):1-14. 10.1186/s12864-019-5444-4 PDF
Pinard D, Fierro AC, Marchal K, Myburg AA, Mizrachi E. (2019) Organellar carbon metabolism is co-ordinated with distinct developmental phases of secondary xylem. New Phytologist 10.1111/nph.15739
Hussey SG, Grima-Pettenati J, Myburg AA, Mizrachi E, Brady SM, Yoshikuni Y, Deutsch S. (2019) A standardized synthetic Eucalyptus transcription factor and promoter panel for re-engineering secondary cell wall regulation in biomass and bioenergy crops. ACS Synthetic Biology 8(2):463-465. 10.1021/acssynbio.8b00440
Wierzbicki MP, Christie N, Pinard D, Mansfield SD, Mizrachi E, Myburg AA. (2019) A systems genetics analysis in Eucalyptus reveals coordination of metabolic pathways associated with xylan modification in wood‐forming tissues. New Phytologist 223(4):1952-1972. 10.1111/nph.15972
Brown K, Takawira L, O'Neill M, Mizrachi E, Myburg A, Hussey S. (2019) Identification and functional evaluation of accessible chromatin associated with wood formation in Eucalyptus grandis. New Phytologist 223(4):1937-1951. 10.1111/nph.15897
Laubscher M, Brown K, Tonfack LB, Myburg AA, Mizrachi E, Hussey SG. (2018) Temporal analysis of Arabidopsis genes activated by Eucalyptus grandis NAC transcription factors associated with xylem fibre and vessel development. Scientific Reports 8:10983. 10.1038/s41598-018-29278-w