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The primary goal of the CTHB is to promote the health of trees native to South Africa through the use of biotechnology. To accomplish this, CTHB projects typically consider the pathogens and pests that are associated with native trees and woody hosts. The CTHB also explores the possible effects that factors such as climate change, society, natural forest health and plant genetics may have on the health of native woody resources and ecosystems.

The CTHB is hosted by the Forestry and Agricultural Biotechnology Institute (FABI) at the University of Pretoria. Within FABI it is intimately linked to the Tree Protection Cooperative Programme (TPCP), a research programme that has a track record of more than two decades in dealing with the pests and diseases of commercially important forestry species.

The CTHB is structured as a virtual Centre of Excellence that conducts scientific research via a collaborative network, with the node of the network represented by researchers at UP. In addition to the UP group, this network involves researchers and their postgraduate students from other Higher Education Institutions in South Africa. These institutions include the Agricultural Research Council, University of Stellenbosch, University of Cape Town, University of the Witwatersrand, University of the Free State and Rhodes University.

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Abate BA, Wingfield MJ, Slippers B, Hurley BP. (2017) Commercialization of Entomopathogenic Nematodes: Should import regulations be revised?. Biocontrol Science and Technology 10.1080/09583157.2016.1278200
Crous PW, Wingfield MJ, Burgess TI, Hardy GESJ, Crane C, Barrett S, Cano-Lira JF, Le Roux JJ, Thangavel R, Guarro J, Stchigel AM, Martín MP, Alfredo DS, Barber PA, Barreto RW, Baseia IG, Cano-Canals J, Cheewangkoon R, Ferreira RJ, Gené J, Lechat C, Moreno G, Roets F, Shivas RG, Sousa JO, Tan YP, Wiederhold NP, Abell SE, Accioly T, Albizu JL, Alves JL, Antoniolli ZI, Aplin N, Araújo J, Arzanlou M, Bezerra JDP, Bouchara J-P, Carlavilla JR, Castillo A, Castroagudín VL, Ceresini PC, Claridge GF, Coelho G, Coimbra VRM, Costa LA, Da Cunha KC, Da Silva SS, Daniel R, De Beer ZW, Dueñas M, Edwards J, Enwistle P, Fiuza PO, Fournier J, García D, Gibertoni TB, Giraud S, Guevara-Suarez M, Gusmão LFP, Haituk S, Heykoop M, Hirooka Y, Hofmann TA, Houbraken J, Hughes DP, Kautmanová I, Koppel O, Koukol O, Larsson E, Latha KPD, Lee DH, Lisboa DO, Lisboa WS, López-Villalba Á, Maciel JLN, Manimohan P, Manjón JL, Marincowitz S, Marney TS, Meijer M, Miller AN, Olariaga I, Paiva LM, Piepenbring M, Poveda-Molero JC, Raj KNA, Raja HA, Rougeron A, Salcedo I, Samadi R, Santos TAB, Scarlett K, Seifert KA, Shuttleworth LA, Silva GA, Silva M, Siqueira JPZ, Souza-Motta CM, Stephenson SL, Sutton DA, Tamakeaw N, Telleria MT, Valenzuela-Lopez N, Viljoen A, Visagie CM, Vizzini A, Wartchow F, Wingfield BD, Yurchenko E, Zamora JC, Groenewald JZ. (2016) Fungal Planet description sheets: 469–557. Persoonia 37:218-403. 10.3767/003158516x694499
McTaggart AR, Shivas RG, Boekhout T, Oberwinkler F, Vánky K, Pennycook SR, Begerow D. (2016) Mycosarcoma (Ustilaginaceae), a resurrected generic name for corn smut (Ustilago maydis) and its close relatives with hypertrophied, tubular sori. IMA Fungus 7(2):309-315. 10.5598/imafungus.2016.07.02.10 PDF
Wingfield BD, Duong TA, Hammerbacher A, van der Nest MA, Wilson A, Chang R, de Beer ZW, Steenkamp ET, Wilken PM, Naidoo K, Wingfield MJ. (2016) IMA Genome-F 7 Draft genome sequences for Ceratocystis fagacearum, C. harringtonii, Grosmannia penicillata, and Huntiella bhutanensis. IMA Fungus 7(2):317-323. 10.5598/imafungus.2016.07.02.11 PDF
Slippers B. (2016) ASSAf and young scientists: Transforming the future of science in South Africa. South African Journal of Science 112:a0189. 10.17159/sajs.2016/a0189 PDF