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PhD student

Department

Microbiology and Plant Pathology
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Primary Supervisor
Lucy Moleleki

Am a PhD student in the Bacterial Genomics and Plant Pathogen Interactions group (HPI), within FABI at the University of Pretoria, under the supervision of Prof. Lucy Moleleki. I completed my MSc in Microbiology at the University of Pretoria in 2015 and my project was focusing on the role of quorum sensing regulon in Pcb .

My research interests are centered on transcriptome profiling using RNA sequencing approach to understand infection processes in pathogen.

Currently, my research is focused on transcriptome profiling of Pectobacterium carotovorum subsp. brasiliense (Pcb) during in planta colonization. An understanding of pathogen responses under host challenge is essential to elucidate the mechanisms of plant-microbe interactions. To date, little is known about the response of Pectobacterium infection to host plants. Specifically, my project will involve RNA sequencing (RNA-Seq) of Pectobacterium carotovorum subsp. brasiliense to unravel the genetic  changes in response to host defense responses.

 

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Publication
Tanui CK, Shyntum DY, Priem SL, Theron J, Moleleki LN. (2017) Influence of the ferric uptake regulator (Fur) protein on pathogenicity in Pectobacterium carotovorum subsp. brasiliense. Plos One 5(12) 10.1371/journal.pone.0177647
Moleleki LN, Pretorius RG, Tanui CK, Mosina G, Theron J. (2016) A quorum sensing‐defective mutant of Pectobacterium carotovorum subsp. brasiliense 1692 is attenuated in virulence and unable to occlude xylem tissue of susceptible potato plant stems. Molecular Plant Pathology 10.1111/mpp.12372