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PhD student

Department

Genetics
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Primary Supervisor
Eshchar Mizrachi

Co Supervisor
Zander Myburg

My MSc project involved the comparative analysis of Carbohydrate Active enZymes (CAZymes) across genomes in the Viridiplantae lineage, along with comparative transcriptome analysis of CAZymes across source and sink tissues in Eucalyptus grandis and Populus trichocarpa. The findings of this project highlighted a conserved mechanism for polysaccharide synthesis, modification and degradation across plant evolution. For my PhD, I am currently working on organelle biology and carbon allocation in wood-forming tissues of Eucalyptus. The focus of my PhD study is the transcriptional regulatory networks of organelle targeted genes in immature xylem of E. grandis and E. urophylla populations, along with the expression profiling of organelle encoded genes in the same populations. Further, a comparative transcriptomic and metabolic analysis of source, sink, and transport tissues in E. urophylla is being analysed in order to construct a comprehensive model of carbon metabolism and partitioning to sub-cellular localizations in wood formation.

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Publication
Pinard DS, Mizrachi E, Hefer C, Kersting AR, Joubert F, Douglas C, Mansfield SD, Myburg AA. (2015) Comparative analysis of plant carbohydrate active enZymes and their role in xylogenesis. BMC Genomics 16:402. 10.1186/s12864-015-1571-8 PDF
Myburg AA, Grattapaglia D, Tuskan GA, Hellsten U, Hayes RD, Grimwood J, Jenkins J, Lindquist E, Tice H, Bauer D, Goodstein DM, Dubchak I, Poliakov A, Mizrachi E, Kullan ARK, Hussey SG, Pinard D, Van der Merwe K, Singh P, et al. (2014) The genome of Eucalyptus grandis. Nature 510:356-362. 10.1038/nature13308
Botha J, Pinard D, Creux N, Hussey S, Maritz-Olivier C, Spokevicius A, Bossinger G, Mizrachi E, Myburg AA. (2011) Characterising the role of the Eucalyptus grandis SND2 promoter in secondary cell wall biosynthesis. BMC Proceedings 5(7):P105. 10.1186/1753-6561-5-S7-P105