Ms Anneri Lötter



PhD student

Department
FABI
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My Supervisor/s

Primary Supervisor
Zander Myburg

As a child I have always wanted to work in a laboratory. Although at that stage I had no knowledge of what that entailed, as I grew up and gathered more information, my interest in the field of biological sciences grew. It was only when I started my undergraduate degree that I was exposed to the various fields of biology. I find biology awe-inspiring, but I also found it striking that we knew so little. The fact remains that we know more about the moon than we know about our own planet, and the systems that drive it. I did my undergraduate degree in Medical Science and my BScHons degree in Genetics. My BScHons project focused on using SNP markers to map the ancestry and the parental species from which chromosomal segments originate within second generation hybrids of Eucalyptus grandis and E. nitens. My BScHons project exposed me to the field of molecular breeding and specifically how some annual crop breeding programs are far more advanced than those used for tree improvement. In order to further explore if such advanced breeding strategies can be implemented I decided to continue with an MSc in Genetics. My MSc project was focused on assembly of phased reference genomes for two Eucalyptus species using a trio-binning approach. During my MSc I went on a research visit to the University of Connecticut to improve my genome assembly bioinformatics skills.

Currently, my PhD project is focused on understanding how structural variation and transposable elements contribute to gene diversity, gene expression and phenotypic diversity observed in E. grandis. My personal aim is to further improve understanding of how haplotype and structural variants contribute to gene expression and the resulting phenotype in Eucalyptus, similar to recent studies in tomato. 

Current research

My current research project is focused on contructing a pan-genome for Eucalyptus grandis and exploring how structural variations and Transposable elements contribute to changes gene expression and resulting phenotypic consequences.

Qualifications

MSc Genetics (2019-2022) - University of Pretoria

BScHons Genetics (2018-2019) - University of Pretoria

BSc Medical Science (2014-2017) - University of Pretoria

Conference outputs

INTERNATIONAL CONFERENCES

  • Anneri Lötter, Tuan A. Duong, Julia Candotti, Eshchar Mizrachi, Jill L. Wegrzyn, Alexander A. Myburg, Structural variation in the haplogenomes of an F1 hybrid of Eucalyptus urophylla and E. grandis, 7 – 9 July 2022, 2022 IUFRO / Forest Tree Molecular Biology and Biotechnology (FTMB) Conference, Harbin, China (Poster presentation).

  • Anneri Lötter, Julia Candotti, Tuan A. Duong, Eshchar Mizrachi, Jill L. Wegrzyn and Alexander A. Myburg, PHASED GENOME ASSEMBLY AND HAPLOGENOME COMPARISON IN AN F1 HYBRID OF EUCALYPTUS UROPHYLLA AND E. GRANDIS, 24 – 27 April 2022, South African Genetics Society and South African Society for Bioinformatics: BIO2022, Western Cape, South Africa (Oral presentation).

  • Anneri Lötter, Julia Candotti, Tuan A. Duong, Eshchar Mizrachi, Jill L. Wegrzyn and Alexander A. Myburg, Structural variant discovery in haplotype resolved genomes of Eucalyptus grandis and E. urophylla, July 19-23, Plant Biology 2021 Worldwide Summit (Poster presentation).

  • Anneri Lötter, Tuan A. Duong, Julia Candotti, Eshchar Mizrachi, Jill L. Wegrzyn and Alexander A. Myburg, Phased assembly of an F1 Eucalyptus urophylla x E. grandis hybrid genome using trio-binning approach, July 17-21, Plant Biology 2020 Worldwide Summit (Poster presentation).

  • Anneri Lötter, Tuan A. Duong, Eshchar Mizrachi, Jill L. Wegrzyn and Alexander A. Myburg, Sequencing and Phased Assembly of an Eucalyptus urophylla x E. grandis F1 Hybrid and Parental Genomes, 11 – 15 January 2020, Plant and Animal Genome XXVIII Conference, San Diego, California, USA (Poster presentation).

     

NATIONAL CONFERENCES

  • Anneri Lötter, Julia Candotti, Tuan A. Duong, Eshchar Mizrachi, Jill L. Wegrzyn and Alexander A. Myburg, Towards haplotype-based genomic breeding: Phased assembly of a Eucalyptus urophylla x E. grandis F1 hybrid genome, 08 – 11 March 2020, 13th Southern African Plant Breeding Symposium 2020, Pretoria, South Africa (Speed talk).

     

 

My Journal Articles

Export to RIS
Publication
Anneri Lötter, Tuan A Duong, Julia Candotti, Eshschar Mizrachi, Jill L Wegrzyn, Alexander A Myburg. (2023) Haplogenome assembly reveals structural variation in Eucalyptus interspecific hybrids. GigaScience 12 10.1093/gigascience/giad064