Dr Thabiso Motaung Motaung
Biochemistry, Genetics and Microbiology
During my Ph.D. in Biotechnology at Free State University (yr 2015), I studied the phenotypic and genetic responses of the major human fungal pathogen Candida albicans to the polyunsaturated fatty molecule, Arachidonic Acid. I subsequently completed postdoctoral studies with the Agricultural Research Council and South African Sugarcane Research Institute, respectively. I joined the academic staff at the University of Pretoria (Department of Biochemistry, Genetics, and Microbiology) in September 2019, as a lecturer and a supervisor for postgraduate research projects.
I am part of a diverse research team based in the Forestry and Agricultural Biotechnology Institute (FABI) of the University of Pretoria. My primary research interest is in understanding the molecular basis of microbial pathogen interaction with forest plants. I investigate the influence on virulence of small non-coding RNA molecules and membrane vesicles in Fusarium circinatum that causes pitch canker disease on pine trees and Douglas fir.
My focus also accommodates many different pathogens including fungi infecting grain crops (e.g., maize, soybeans, sunflower, etc.) produced in the summer rainfall regions of South Africa. Many pathogenic species of fungi account for substantial yield losses in major grain crops through different infection strategies, but the influence of biofilms – the architecturally complex communities glued together by a matrix – has largely been underemphasized. Therefore, I want to understand how fungi, through such crowded cell communities, exploit emerging ecological opportunities to cause infections in crops such as maize. I pursue this research question through the membership of the new Grain Research Programme developed by FABI in collaboration with GrainSA and other stakeholder departments.
Bacterial Genetics (MBY 355)
Genetic Manipulation of Microbes (MBY 364)
Project Proposal, Trends in Microbiology, and Joint Techniques course
Currently serving in the capacities mentioned below:
- 2021-present: ASAPbio (Accelerating Science and Publication in biology) Board of Directors;
- 2021-present: Review Editor for Frontiers in Plant Science and Frontiers in Microbiology;
- 2020-present: Ethics division coordinator for the University of Pretoria;
- 2017-present: Reviewer, GMO Advisory committee, National Department of Forestry, Fisheries and the Environment (Ministerial appointment);
- Peer reviewer at various science journals.
My Journal Articles
|Thabiso E Motaung, Emma T Steenkamp. (2021) Extracellular Vesicles in Teasing Apart Complex Plant-Microbiota Links: Implications for Microbiome-Based Biotechnology. mSystems 6(4):e00734-21.
|Jane Chepsergon, Thabiso E. Motaung, Lucy Novungayo Moleleki. (2021) “Core” RxLR effectors in phytopathogenic oomycetes: A promising way to breeding for durable resistance in plants?. Virulence 12(1):1921-1935.
|Motaung TE, Peremore C, Wingfield BD, Steenkamp ET. (2020) Plant-associated fungal biofilms – knowns and unknowns. FEMS Microbiology Ecology
|Chepsergon J, Motaung TE, Bellieny-Rabelo D, Moleleki LN. (2020) Organize, Don’t Agonize: Strategic Success of Phytophthora Species. Microorganisms 8(6):917.
|Motaung TE. (2020) Chloronicotinyl insecticide imidacloprid: Agricultural relevance, pitfalls and emerging opportunities. Crop Protection 131:105097.
|Motaung TE. (2018) Cryptococcus neoformans mutant screening: a genome-scale's worth of function discovery. Fungal Biology Reviews 32(3):181-203.
|Motaung TE, Ells R, Pohl CH, Albertyn J, Tsilo JT. (2017) Genome-wide functional analysis in Candida albicans. Virulence 8(8):1563-1579.
|Dweba CC, Figlan S, Shimelis HA, Motaung TE, Sydenham S, Mwadzingeni L. (2017) Fusarium head blight of wheat: Pathogenesis and control strategies. Crop Protection 91:114-122.
|Motaung TE, Saitoh H, Tsilo T. (2017) Large‐scale molecular genetic analysis in plant‐pathogenic fungi: a decade of genome‐wide functional analysis. Molecular Plant Pathology 18(5):754-764.
|Motaung TE, Petrovski KR, Petzer I-M, Thekisoe O. (2017) Importance of bovine mastitis in Africa. Animal Health Research Reviews 18(1):58-69.
|Motaung TE, Albertyn J, Pohl CH. (2015) Candida albicans mutant construction and characterization of selected virulence determinants. Journal of Microbiological Methods 115:153-165.
|Motaung TE, Albertyn J, Kock JLF, Lee C-F, Suh S-O, Blackwell M, Pohl CH. (2013) Trichosporon vanderwaltii sp. nov., an asexual basidiomycetous yeast isolated from soil and beetles. Antonie Van Leeuwenhoek 103(2):313-319.
|Motaung TE, Albertyn J, Kock JLF, Pohl CH. (2012) Cryptococcus cyanovorans sp. nov., a basidiomycetous yeast isolated from cyanide-contaminated soil. International Journal of Systematic and Evolutionary Microbiology 62(5):1208-1214.
My News and Views Articles
|Motaung TE. (2017) Use of mutant collections to understand pathogenicity in economically important fungi. SA Grain :1.